Even though slavery was abolished over a hundred years ago human trafficking remains a vast global problem. Despite international agreements and a plethora of national laws on the issue it remains one of the fastest growing criminal trades in the world. Due to its cross border nature human trafficking requires cooperation and collaboration between states, if it is to be tackled effectively. However, throughout the world often anti-trafficking initiatives have failed to incorporate all stakeholders in the fight against human trafficking. The Meghalaya model is a multi-sector approach involving government, law enforcement, judiciary and civil society organisations that creates a comprehensive framework for combating trafficking of girls under the five “Ps” Prevention, Protection, Policing, Press and Prosecution. This idea addresses under utilisation of resources by the different stakeholders by creating a a formal network of organisations situated in strategic locations to co-ordinate a response to human trafficking cases within the North East region. The model’s different initiatives aim to track and rescue trafficked children, facilitate rehabilitation, provide families with livelihood alternatives, prosecute offenders, and raise awareness on the issue. This holistic approach does not just see human trafficking as confined to a problem of law enforcement but understands that it is a result of wider socio-economic factors which have to be addressed.